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Gossypol, 98+%

Catalog No. p-7042790
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Quantity:
100 mg
250 mg
Catalog No. Quantity
AAJ63767MC 100 mg
AAJ63767MD 250 mg
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Catalog No. AAJ63767MC

Supplier: Thermo Scientific Chemicals J63767MC

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Description

Lipophilic agent derived from cottonseed | CAS: 303-45-7 | C30H30O8 | 518.56 g/mol

Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.

Solubility
Soluble in 100%ethanol (25 mg/ml), DMF (25 mg/ml), acetone, DMSO (25 mM), methanol (2 mg/ml), ether, chloroform, sodium carbonate, and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor, anitviral, and antioxidant properties.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Chemical Identifiers

CAS 303-45-7
Molecular Formula C30H30O8
Molecular Weight (g/mol) 518.56
MDL Number MFCD00017352
InChI Key QBKSWRVVCFFDOT-UHFFFAOYSA-N
Synonym gossypol, --gossypol, +-gossypol, pogosin, tash 1, racemic-gossypol, r---gossypol, r-gossypol, +--gossypol, +/--gossypol
PubChem CID 3503
ChEBI CHEBI:28584
SMILES CC(C)C1=C(O)C(O)=C(C=O)C2=C(O)C(=C(C)C=C12)C1=C(O)C2=C(C=O)C(O)=C(O)C(C(C)C)=C2C=C1C

Specifications

Color Yellow to Brown
Quantity 100 mg
Merck Index 14,4528
Solubility Information Soluble in 100%ethanol (25mg/ml),DMF (25mg/ml),acetone,DMSO (25 mM),methanol (2mg/ml),ether,chloroform,sodium carbonate,and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor,anitviral,and antioxidant properties.
IUPAC Name 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
Formula Weight 518.56
Percent Purity ≥98%
Physical Form Powder
Chemical Name or Material Gossypol

Safety and Handling

Hazard Category H302-H341-H361
Hazard Statement GHS H Statement
H341-H361-H302
Suspected of causing genetic defects.
Suspected of damaging fertility or the unborn child.
Harmful if swallowed.
Precautionary Statement P201-P202-P264b-P270-P281-P301+P312-P308+P313-P330-P501c
RTECSNumber DU3100000
TSCA No
Recommended Storage Store at -20°C

RUO – Research Use Only