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Invitrogen™ GLI2 Polyclonal Antibody

Catalog No. PIPA540443
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100 μL
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Catalog No. Quantity
PIPA540443 100 μL
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Catalog No. PIPA540443 Supplier Invitrogen™ Supplier No. PA540443

Description

Rabbit Polyclonal Antibody

Peptide sequence: RNDVHLRTPL LKENGDSEAG TEPGGPESTE ASSTSQAVED CLHVRAIKTE Sequence homology: Human: 100%.

Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Specifications

Antigen GLI2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene GLI2
Gene Accession No. P10070, Q0VGT2
Gene Alias AW546128; CJS; GLI family zinc finger 2; GLI family zinc finger protein 2; GLI2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; HPE9; oncogene GLI2; PHS2; Tax helper protein; tax helper protein 1; tax helper protein 2; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein; Thp; THP1; THP2; zinc finger protein GLI2
Gene Symbols GLI2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human GLI2 (aa 600-649).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14633, 2736
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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