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Invitrogen™ GLDC Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA522102
Description
Recommended positive controls: HePG2. Predicted reactivity: Mouse (91%), Rat (84%), Xenopus laevis (86%), Chicken (85%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).Specifications
| GLDC | |
| Polyclonal | |
| Unconjugated | |
| GLDC | |
| D030049L12Rik; D19Wsu57e; GCE; GCSP; GLDC; Glycine cleavage system P protein; glycine cleavage system protein P; glycine decarboxylase; glycine decarboxylase P-protein; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial; HYGN1; RP11-472F14.1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 104174, 2731, 309312 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 0.46 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P23378, Q91W43 | |
| GLDC | |
| Recombinant protein encompassing a sequence within the center region of human Glycine dehydrogenase. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |