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  6. Invitrogen™ GCK Recombinant Rabbit Monoclonal Antibody (23GB5845)

Invitrogen™ GCK Recombinant Rabbit Monoclonal Antibody (23GB5845)

Catalog No. MA552929
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100 μL
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MA552929 20 μL
MA552928 100 μL
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Catalog No. MA552929 Supplier Invitrogen™ Supplier No. MA552929
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Description

Rabbit Recombinant Monoclonal Antibody

GCK Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Specifications

Antigen GCK
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB5845
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GCK
Gene Accession No. P35557
Gene Alias ATP:D-hexose 6-phosphotransferase; FGQTL3; GC kinase; Gck; Gk; GLK; Gls006; glucokinase; glucokinase (hexokinase 4); glucokinase variant 3; GLUKA; hexokinase 4; hexokinase D, pancreatic isozyme; hexokinase type IV; Hexokinase-4; hexokinase-D; HHF3; HK IV; HK4; HKIV; Hlb62; HXKP; LGLK; MEKKK 2; MODY2; RNGK2
Gene Symbols GCK
Host Species Rabbit
Immunogen A synthesized peptide derived from human Glucokinase (250-465AA).
Purification Method Affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2645
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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