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Invitrogen™ Ganglioside GM2 Chimeric Recombinant Rabbit Monoclonal Antibody (KM966)
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Catalog No. MA551582
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200 μg
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Catalog No. Quantity
MA551582 200 μg
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Catalog No. MA551582 Supplier Invitrogen™ Supplier No. MA551582
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: This antibody recognizes and binds ganglioside GM2.

Ganglioside GM2 is a glycosphingolipid found in the plasma membrane of cells, particularly in the nervous system. It is composed of a ceramide lipid tail and a complex carbohydrate head group that contains sialic acid residues. The function of Ganglioside GM2 is not fully understood, but it is believed to play a role in cell signaling and communication, as well as in the formation and maintenance of the myelin sheath that surrounds nerve cells. Mutations in the genes responsible for the synthesis or degradation of Ganglioside GM2 can result in various neurological disorders, including Tay-Sachs disease and Sandhoff disease.

Specifications

Antigen Ganglioside GM2 Chimeric
Applications ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry
Classification Recombinant Monoclonal
Clone KM966
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Host Species Rabbit
Immunogen This chimeric antibody was generated by cloning the variable heavy and light chain sequences of murine parent antibody KM696 (IgM) and expressing it as a mouse/human IgG1. The parent antibody was raised against human GM2.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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