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Invitrogen™ GAK Polyclonal Antibody
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Catalog No. PIPA599201
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100 μL
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Catalog No. Quantity
PIPA599201 100 μL
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Catalog No. PIPA599201 Supplier Invitrogen™ Supplier No. PA599201
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GAK.

GAK serine/threonine kinase or Cyclin-G-associated kinase was originally identified as a protein that is associated with cyclin G. However, neither CDK5 nor GAK kinase activity is activated by cyclin G nor does GAK affect CDK5 kinase activity. GAK seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

Specifications

Antigen GAK
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GAK
Gene Accession No. O14976, Q99KY4
Gene Alias auxilin-2; cyclin G associated kinase; cyclin G-associated kinase; cyclin-G-associated kinase; D130045N16Rik; DNAJ26; DNAJC26; GAK
Gene Symbols GAK
Host Species Rabbit
Immunogen A synthesized peptide derived from human GAK(Accession O14976), corresponding to amino acid residues K109-V159.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 231580, 2580
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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