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Invitrogen™ Human Fractalkine ProQuantum Immunoassay Kit 
ELISA
$990.00 - $4150.00
Specifications
| Accession Number | P78423 |
|---|---|
| Assay Range | 0.0064 to 500 pg/mL |
| Assay Sensitivity | <0.005 pg/mL |
| Conjugate | FAM™ |
| Detection Method | Taqman™ Real-time PCR |
Description
Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.Specifications
| P78423 | |
| <0.005 pg/mL | |
| Taqman™ Real-time PCR | |
| ProQuantum | |
| Human | |
| qPCR Instruments | |
| ABCD-3; C3Xkine; CXC3; CXC3C; NTN; NTT; SCYD1; fractalkine; neurotactin | |
| Assay Dilution Buffer, Antibody-Conjugate A, Antibody-Conjugate B, Antibody-Conjugate Dilution Buffer, Standard, Master Mix, Ligase | |
| RUO | |
| Frozen at -20°C | |
| 30 mins |
| 0.0064 to 500 pg/mL | |
| FAM™ | |
| Proximity-based Immunoassay | |
| Plasma, Serum, Supernatant | |
| Protein Quantitation | |
| 6376 | |
| 1 hr. | |
| FAM™ | |
| Plasma 2-5 μL, Serum 2-5 μL, Supernatant 2-5 μL | |
| CX3CL1 | |
| 2 hrs |