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Invitrogen™ FLAP Recombinant Rabbit Monoclonal Antibody (2S7Z0)
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Catalog No. PIMA537933
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100 μL
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Catalog No. Quantity
PIMA537933 100 μL
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Catalog No. PIMA537933 Supplier Invitrogen™ Supplier No. MA537933
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: A-549, THP-1, U-937 Immunogen sequence: DAYPTFLAVL WSAGLLCSQV PAAFAGLMYL FVRQKYFVGY LGERTQSTPG YIFGKRIILF LFLMSVAGIF NYYLIFFFGS DFENYIKTIS TTISPLLLIP.

ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Specifications

Antigen FLAP
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 2S7Z0
Concentration 0.58 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ALOX5AP
Gene Accession No. P20292
Gene Alias 5-lipoxygenase-activating protein FLAP; Alox5ap; arachidonate 5-lipoxygenase activating protein; arachidonate 5-lipoxygenase-activating protein; Flap; MK-886-binding protein
Gene Symbols ALOX5AP
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 241
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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