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Invitrogen™ Human FGFR2, His Tag Recombinant Protein

Catalog No. PR5332A
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100 μg
1 mg
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PR5332A 100 μg
PV4106 1 mg
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Catalog No. PR5332A Supplier Invitrogen™ Supplier No. PR5332A
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Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Catalytic Domain, Cytoplasmic.

FGFR2 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR family members differ from one another in their ligand affinities and tissue distribution. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Specifications

Accession Number P21802
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris with 150mM NaCl, 50% glycerol, 0.5mM EDTA, 0.04% Triton X-100, 4mM DTT and no preservative; pH 7.5
Gene ID (Entrez) 2263
Molecular Weight (g/mol) 52.1 kDa
Name Human FGFR2, His Tag
pH Range 7.5
Purification Method Purified
Quantity 100 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias AU043015; AW556123; bacteria-expressed kinase; BBDS; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; ECT1; FGF Receptor; FGF Receptor 2; FGF-10; FGFR; FGFR2; FGFR-2; Fgfr7; Fgfr-7; fibroblast growth factor receptor 2; JWS; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-SAM; protein tyrosine kinase, receptor like 14; Soluble KGFR; svs; TK14; TK25
Common Name FGFR2
Gene Symbol FGFR2
KinaseFamily FGF Receptor Kinase Family
Protein Length 403-822
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-tag
Sequence 403-822
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Tyrosine Kinases
Shipping Condition Dry Ice
Expression System Baculovirus
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Catalytic Domain, Cytoplasmic
Form Liquid
Protein Subtype Kinases & Inhibitors
Research Category Oncology
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