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  6. Invitrogen™ FDPS Recombinant Rabbit Monoclonal Antibody (23GB1395)

Invitrogen™ FDPS Recombinant Rabbit Monoclonal Antibody (23GB1395)
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Catalog No. MA553978
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MA553978 100 μL
MA553979 20 μL
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Catalog No. MA553978 Supplier Invitrogen™ Supplier No. MA553978

Description

Rabbit Recombinant Monoclonal Antibody

FDPS Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes. 1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.

Specifications

Antigen FDPS
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB1395
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene FDPS
Gene Accession No. P14324
Gene Alias (2E,6E)-farnesyl diphosphate synthase; 6030492I17Rik; Ac2-125; AI256750; cholesterol-regulated 39 kDa protein; CR 39; dimethylallyltranstransferase; Farnesyl diphosphate synthase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); farnesyl diphosphate synthetase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; Fdps; Fdpsl1; FPP synthase; FPP synthetase; FPPS; FPS; geranyltranstransferase; KIAA1293; mKIAA1293; POROK9; testis-specific farnesyl pyrophosphate synthetase
Gene Symbols FDPS
Host Species Rabbit
Immunogen A synthesized peptide derived from human FDPS (370-410AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2224
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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