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FBW7 Rabbit anti-Human, Polyclonal, Bethyl Laboratories 
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories Inc A301720A
Description
The recommended shelf life for this product is 1 year from date of receipt.
Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of maligcies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.Specifications
| FBW7 | |
| Polyclonal | |
| Unconjugated | |
| FBXW7 | |
| AGO, archipelago, Archipelago homolog, archipelago homolog (Drosophila), CDC4, F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase, F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila), F-box and WD-40 domain-containing protein 7, F-box protein FBW7, F-box protein FBX30, F-box protein SEL-10, FBW6, FBW7, FBX30, FBXO30, FBXW6, FLJ11071, hAgo, hCdc4, homolog of C elegans sel-10, SEL10, SEL-10 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 55294 | |
| 4° C | |
| Liquid |
| Immunoprecipitation | |
| 1 mg/ml | |
| phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
| Q969H0 | |
| FBXW7 | |
| Between 1 and 50 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |