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Invitrogen™ FANCL Polyclonal Antibody
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Catalog No. PIPA557769
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PIPA557769 100 μL
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Catalog No. PIPA557769 Supplier Invitrogen™ Supplier No. PA557769

Description

Rabbit Polyclonal Antibody

Immunogen sequence: FPARAILEKS DFTMDCGICY AYQLDGTIPD QVCDNSQCGQ PFHQICLYEW LRGLLTSRQS FNIIFGECPY CSKPIT Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 80%.

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.

Specifications

Antigen FANCL
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FANCL
Gene Accession No. Q9NW38
Gene Alias 2010322C19Rik; AW554273; B230118H11Rik; E3 ubiquitin-protein ligase FANCL; FA complementation group L; FAAP43; FANCL; Fanconi anemia complementation group L; fanconi anemia group L protein; Fanconi anemia group L protein homolog; Fanconi anemia, complementation group L; fanconi anemia-associated polypeptide of 43 kDa; FLJ10335; gcd; germ cell deficient; PHD finger protein 9; Phf9; Pog; proliferation of germ cells protein; RING-type E3 ubiquitin transferase FANCL
Gene Symbols FANCL
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FANCL. Recombinant protein control fragment (Product #RP-96016).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55120
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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