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Everolimus

A rapamycin analog | CAS: 159351-69-6 | C53H83NO14 | 958.24 g/mol

Supplier:  Thermo Scientific Chemicals J60139MA

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Catalog No. AAJ60139MA


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Description

Description

Everolimus is a rapamycin analog. It is used to treat certain types of kidney cancer, breast cancer and brain tumor. It prevents transplant rejection by decreasing the activity of the immune system. It also act as a kinase inhibitor. It is used in the treatment of subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.

Notes
Incompatible with strong oxidizing agents.
Specifications

Specifications

Everolimus
White
MFCD07785165
14,3907
HKVAMNSJSFKALM-PWMUVMERSA-N
958.24
958.22
159351-69-6
C53H83NO14
10 mg
Soluble in dimethysulfoxide,ethanol and chloroform; Slightly soluble in water.
CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC
129317877
Powder

Chemical Identifiers

159351-69-6
958.24
HKVAMNSJSFKALM-PWMUVMERSA-N
CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC
C53H83NO14
MFCD07785165
129317877
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Safety and Handling

Safety and Handling

GHS H Statement
H372
Causes damage to organs through prolonged or repeated exposure.

P260-P264b-P270-P314-P501c

H372

TSCA : No

Recommended Storage : Store at -20°C

SDS
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RUO – Research Use Only