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PeproTech Eotaxin 3 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Catalog No. P156GBT25
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25 μg
50 μg
500 μg
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Catalog No. Quantity
P156GBT25 25 μg
P156GBT50 50 μg
502718658 500 μg
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Catalog No. P156GBT25 Supplier PeproTech Supplier No. 500P156GBT25UG
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Description

Goat Polyclonal Antibody

AA Sequence of recombinant protein: TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L. Preparation: Produced from sera of goats immunized with highly pure Recombinant Human Eotaxin-3 (CCL26). Anti-hEotaxin-3 (CCL26)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect hEotaxin-3 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human Eotaxin-3 (500-P156G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hEotaxin-3. Western Blot: To detect hEotaxin-3 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hEotaxin-3 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P156GBT-1MG will be provided as 2 x 500 μg

Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.

Specifications

Antigen Eotaxin 3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.1-1.0 mg/mL
Conjugate Biotin
Formulation PBS with no preservative
Gene CCL26
Gene Accession No. Q9Y258
Gene Alias CC chemokine IMAC; C-C motif chemokine 26; C-C motif chemokine ligand 26; Ccl26; Ccl26l; chemokine (C-C motif) ligand 26; chemokine N1; Eotaxin3; eotaxin-3; IMAC; Macrophage inflammatory protein 4-alpha; MGC126714; MIP-4a; MIP-4alpha; MIP-4-alpha; PRO242; SCYA26; SCYA26MIP-4-alpha; small inducible cytokine A26; small inducible cytokine subfamily A (Cys-Cys), member 26; small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; UNQ216; UNQ216/PRO242
Gene Symbols CCL26
Host Species Goat
Immunogen E.coli-derived Recombinant Human Eotaxin-3 (CCL26).
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10344
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
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