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EOMES Monoclonal Antibody (WD1928), Alexa Fluor™ 660, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$304.00 - $638.00
Specifications
| Antigen | EOMES |
|---|---|
| Clone | WD1928 |
| Concentration | 5 μL/Test |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
Description
The WD1928 antibody recognizes Eomesodermin (Eomes), also known as T-box brain 2 (TBR2). Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates. In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells. Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R.
TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.Specifications
| EOMES | |
| 5 μL/Test | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with BSA and 0.09% sodium azide; pH 7.2 | |
| C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2 | |
| Eomes | |
| Primary | |
| 4°C, store in dark, DO NOT FREEZE! | |
| Eomes |
| WD1928 | |
| Flow Cytometry | |
| Alexa Fluor 660 | |
| Mouse | |
| Human, Pig | |
| O95936 | |
| 100622125, 8320 | |
| IgG1 κ | |
| Affinity chromatography | |
| Antibody |