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Enalaprilat
The active metabolite of enalapril | CAS: 76420-72-9 | C18H24N2O5 | 348.399 g/mol
$279.19 - $805.34
Chemical Identifiers
| CAS | 76420-72-9 |
|---|---|
| Molecular Formula | C18H24N2O5 |
| Molecular Weight (g/mol) | 348.399 |
| MDL Number | MFCD00865786 |
| InChI Key | LZFZMUMEGBBDTC-QEJZJMRPSA-N |
| Synonym | enalaprilat, enalapril acid, enalaprilate, enalaprilatum, enalapril diacid, enalaprilic acid, enalaprilat anhydrous, n-1s-1-carboxy-3-phenylpropyl-l-alanyl-l-proline, unii-q508q118jmShow More |
| PubChem CID | 5462501 |
| ChEBI | CHEBI:4786 |
| IUPAC Name | (2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid |
| SMILES | CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ63392MA
|
Thermo Scientific Chemicals
J63392MA |
10 mg |
Each for $279.19
|
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AAJ63392MF
|
Thermo Scientific Chemicals
J63392MF |
50 mg |
Each for $805.34
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Description
Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril (sc-200566). Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsEnalapril is a ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril (sc-200566). Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.
Solubility
Soluble in water with heating (∼60°C)
Notes
Store in a cool dry place. Keep away from oxidizing agents.
Chemical Identifiers
| 76420-72-9 | |
| 348.399 | |
| LZFZMUMEGBBDTC-QEJZJMRPSA-N | |
| 5462501 | |
| (2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acidShow More |
| C18H24N2O5 | |
| MFCD00865786 | |
| enalaprilat, enalapril acid, enalaprilate, enalaprilatum, enalapril diacid, enalaprilic acid, enalaprilat anhydrous, n-1s-1-carboxy-3-phenylpropyl-l-alanyl-l-proline, unii-q508q118jmShow More | |
| CHEBI:4786 | |
| CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O |
Specifications
| 76420-72-9 | |
| White | |
| MFCD00865786 | |
| 14,3568 | |
| Soluble in water with heating (∽60°C) | |
| CC(C(=O)N1CCCC1C(=O)O)NC(CCC2=CC=CC=C2)C(=O)O | |
| 348.399 | |
| CHEBI:4786 | |
| Crystalline Solid |
| 148°C to 151°C | |
| C18H24N2O5 | |
| 10 mg | |
| enalaprilat, enalapril acid, enalaprilate, enalaprilatum, enalapril diacid, enalaprilic acid, enalaprilat anhydrous, n-1s-1-carboxy-3-phenylpropyl-l-alanyl-l-proline, unii-q508q118jm | |
| LZFZMUMEGBBDTC-QEJZJMRPSA-N | |
| (2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid | |
| 5462501 | |
| 384.42 | |
| Enalaprilat |
Safety and Handling
EINECSNumber : 278-459-3
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only