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MilliporeSigma™ MMP-1, Proenzyme, Human Rheumatoid Synovial Fibroblast, Protein
Supplier: MilliporeSigma™ 4442085UG
Description
Native proMMP-1 from cultured, human rheumatoid synovial fibroblast. Corresponds to the 56kDa/52kDa enzyme. May contain some activated enzyme but requires activation by APMA for 30 - 60 min. at 30°C just prior to use to obtain fully activated enzyme (46kDa/42kDa). May also undergo autocatalysis to yield a 27kDa/22kDa active enzyme. Expressed by a large number of cell types. Cleaves fibrillar type I collagen.Specifications
| Concentration on Label | |
| SDS-PAGE | |
| MMP-1 | |
| RUO | |
| Native | |
| ≥90% |
| In 300mM NaCl, 50mM Tris-HCl, 5mM CaCl2, 1μM ZnCl2, 0.05% BRIJ™ 35 Detergent, 0.05% NaN3, pH 7.0. | |
| 5 μg | |
| Following initial thaw, aliquot and freeze (−70°C). | |
| Human | |
| Liquid |