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MilliporeSigma™ Cathepsin D, Human Liver, Protein
Supplier: MilliporeSigma™ 21940130U
Description
Native cathepsin D from human liver. A major lysosomal aspartyl protease produced as a 52kDa proenzyme. Overexpression of cathepsin D in human breast cancers is associated with higher risk of relapse and metastasis. Cathepsin D degrades extracellular matrix and releases growth factors bound to the matrix.Specifications
| Lyophilized from 2mM sodium phosphate buffer, pH 6.5. | |
| SDS-PAGE | |
| Cathepsin D | |
| RUO | |
| Native | |
| ≥90% |
| Sterile H2O or aqueous buffers. Please see vial label for lot-specific reconstitution volume. | |
| 30 U | |
| Following reconstitution, aliquot and freeze (−20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C. Keep on ice when working with material. When product is brought to its active pH (3.3), autolysis occurs. | |
| Human | |
| Lyophilized |