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MilliporeSigma™ Angiostatin K1-3, Human, Recombinant Protein, E. coli

Supplier:  MilliporeSigma™ 176708250UG

Catalog No. 17-670-8250UG


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Description

Description

Recombinant, human angiostatin expressed in E. coli as a single, nonglycosylated polypeptide chain containing 259 amino acids. Represents a proteolytic fragment containing the first three kringle structures of plasminogen. Acts as a specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50=135nm).
Specifications

Specifications

Lyophilized from 20mM Sodium Acetate, 4% Mannitol, pH 5.5.
HPLC and SDS-PAGE
E. coli
Following reconstitution, aliquot and freeze (−20°C). Stock solutions are stable for up to 6 months at −20°C.
Human
Lyophilized
H2O or Aqueous Buffer Containing 0.1% BSA
250 μg
Angiostatin K1-3
RUO
Recombinant
≥95%
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