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MilliporeSigma™ Angiostatin K1-3, Human, Recombinant Protein, E. coli
Description
Recombinant, human angiostatin expressed in E. coli as a single, nonglycosylated polypeptide chain containing 259 amino acids. Represents a proteolytic fragment containing the first three kringle structures of plasminogen. Acts as a specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50=135nm).
Specifications
Specifications
| Formulation | Lyophilized from 20mM Sodium Acetate, 4% Mannitol, pH 5.5. |
| Preparation Method | H2O or Aqueous Buffer Containing 0.1% BSA |
| Purification Method | HPLC and SDS-PAGE |
| Quantity | 250 μg |
| Source | E. coli |
| Immunogen | Angiostatin K1-3 |
| Storage Requirements | Following reconstitution, aliquot and freeze (−20°C). Stock solutions are stable for up to 6 months at −20°C. |
| Regulatory Status | RUO |
| Species | Human |
| Recombinant | Recombinant |
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