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Invitrogen™ ECH1 Monoclonal Antibody (9D11AF3)

Description
ECH1 Monoclonal Antibody for ICC/IF, IP, ELISA
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Specifications
Specifications
| Antigen | ECH1 |
| Applications | ELISA, Immunoprecipitation, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 9D11AF3 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | HEPES buffered saline with 0.02% sodium azide |
| Gene | ECH1 |
| Gene Accession No. | Q13011, Q62651 |
| Gene Alias | AA617331; delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; delta3,5-delta2,4-dienoyl-CoA isomerase; delta3,5-delta2,4-dienoyl-coenzyme A isomerase; dienoyl-CoA isomerase; ECH1; enoyl CoA hydratase 1, peroxisomal; enoyl coenzyme A hydratase 1, peroxisomal; enoyl hydratase-like protein peroxisomal; enoyl hydratase-like protein, peroxisomal; enoyl-CoA hydratase 1; enoyl-CoA hydratase 1, peroxisomal; HPXEL; Peroxisomal enoyl hydratase-like protein; peroxisomal enoyl-CoA hydratase 1; peroxisomal/mitochondrial dienoyl-CoA isomerase; Pxel |
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