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Invitrogen™ E2F2 Recombinant Rabbit Monoclonal Antibody (23GB5250)
Rabbit Recombinant Monoclonal Antibody
$590.92 - $1,416.21
Specifications
| Antigen | E2F2 |
|---|---|
| Clone | 23GB5250 |
| Concentration | 2 mg/mL |
| Content And Storage | -20°C |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
Description
E2F2 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot
E2F2 is a member of the E2Ffamily of transcription factors. The E2F family plays a crucialrole in the control of cell cycle and action of tumor suppressorproteins and is also a target of the transforming proteins of smallDNA tumor viruses. The E2F proteins contain several evolutionallyconserved domains found in most members of the family. Thesedomains include a DNA binding domain, a dimerization domain whichdetermines interaction with the differentiation regulatedtranscription factor proteins (DP), a transactivation domainenriched in acidic amino acids, and a tumor suppressor proteinassociation domain which is embedded within the transactivationdomain. This protein and another 2 members, E2F1 and E2F3, have anadditional cyclin binding domain. This protein binds specificallyto retinoblastoma protein pRB in a cell-cycle dependent manner, andit exhibits overall 46% amino acid identity to E2F1.Specifications
| E2F2 | |
| 2 mg/mL | |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P56931, Q14209 | |
| 1870, 242705, 684111 | |
| A synthesized peptide derived from human E2F2 (313-375AA). | |
| Antibody |
| 23GB5250 | |
| -20°C | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| E2F2 | |
| E2F transcription factor 2; E2F2; E2F-2; LOW QUALITY PROTEIN: transcription factor E2F2; transcription factor E2F2 | |
| E2F2 | |
| Primary | |
| Affinity chromatography |