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  6. Invitrogen™ DTYMK Recombinant Rabbit Monoclonal Antibody (23GB5235)

Invitrogen™ DTYMK Recombinant Rabbit Monoclonal Antibody (23GB5235)
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Catalog No. MA553870
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100 μL
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MA553870 100 μL
MA553871 20 μL
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Description

Rabbit Recombinant Monoclonal Antibody

DTYMK Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.

Specifications

Antigen DTYMK
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB5235
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DTYMK
Gene Accession No. P23919
Gene Alias AU044245; CDC8; D10Ertd203e; deoxythymidylate kinase; deoxythymidylate kinase (thymidylate kinase); dTMP kinase; DTYMK; mtmk; PP3731; Thymidylate kinase; Tmk; TMPK; TYMK; TYPK
Gene Symbols DTYMK
Host Species Rabbit
Immunogen A synthesized peptide derived from human DTYMK (160-200AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1841
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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