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  6. Invitrogen™ DTX3L Monoclonal Antibody (K24022_12C6), Invitrogen™

Invitrogen™ DTX3L Monoclonal Antibody (K24022_12C6), Invitrogen™

Catalog No. MA556194
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50 μL
200 μL
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MA556194 200 μL
MA555814 50 μL
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Catalog No. MA556194 Supplier Invitrogen™ Supplier No. MA556194
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Description

Mouse Monoclonal Antibody

Sequence of this protein is as follows: RVRRKLESYF QSSKSSGGGE CTVSTQEHEA PGTFRVEFSE RAAKERVLKK GEHQILVDEK PVPIFLVPTE NSIKKNTRPQ ISSLTQSQAE TPSGDMHQHE

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.

Specifications

Antigen DTX3L
Applications Western Blot
Classification Monoclonal
Clone K24022_12C6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene DTX3L
Gene Accession No. Q8TDB6
Gene Alias AU042200; Bbap; BC023741; B-lymphoma- and BAL-associated protein; deltex 3 like, E3 ubiquitin ligase; deltex 3-like; deltex 3-like (Drosophila); deltex E3 ubiquitin ligase 3L; DTX3L; E3 ubiquitin-protein ligase DTX3L; Protein deltex-3-like; RGD1565144; rhysin 2; Rhysin2; rhysin-2; RING-type E3 ubiquitin transferase DTX3L
Gene Symbols DTX3L
Host Species Mouse
Immunogen Recombinant human DTX3L (immunogen range is 21-120).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 151636
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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