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Invitrogen™ DOK7 Polyclonal Antibody
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Catalog No. pipa5101181
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PIPA5101181 100 μL
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Catalog No. PIPA5101181 Supplier Invitrogen™ Supplier No. PA5101181
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total DOK7.

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.

Specifications

Antigen DOK7
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DOK7
Gene Accession No. Q18PE0, Q18PE1
Gene Alias A930013K19Rik; AW049091; C4orf25; CMS10; CMS1B; docking protein 7; DOK7; Dok-7; Downstream of tyrosine kinase 7; EF-12; Oit5; oncoprotein induced transcript 5; protein Dok-7; RGD1566416
Gene Symbols DOK7
Host Species Rabbit
Immunogen A synthesized peptide derived from human DOK7(Accession Q18PE1), corresponding to amino acid residues P415-T465.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 231134, 285489
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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