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DL-Thiorphan

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AAJ62557MB 25 mg
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Catalog No. AAJ62557MB Supplier Thermo Scientific Chemicals Supplier No. J62557MB
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Description

CAS: 76721-89-6 | C12H15NO3S | 253.32 g/mol

Thiorphan has the ability to block the degradation of the luteinizing hormone releasing hormone (LHRH). At higher concentrations, (14 ?M) this compound has been shown to inhibit the activity of angiotensin-converting enzyme (ACE). Neprilysin is overexpressed in many forms of cancer and may play a role in protecting against Alzheimer’s disease.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiorphan has the ability to block the degradation of the luteinizing hormone releasing hormone (LHRH). At higher concentrations, (14 μM) this compound has been shown to inhibit the activity of angiotensin-converting enzyme (ACE). N

Chemical Identifiers

CAS 76721-89-6
Molecular Formula C12H15NO3S
Molecular Weight (g/mol) 253.32
MDL Number MFCD00058435
InChI Key LJJKNPQAGWVLDQ-UHFFFAOYNA-N
Synonym thiorphan, dl-thiorphan, dl-3-mercapto-2-benzylpropanoylglycine, n-2-benzyl-3-sulfanylpropanoyl glycine, chembl10247, glycine, n-2-mercaptomethyl-1-oxo-3-phenylpropyl-, +-, 2-2-benzyl-3-sulfanylpropanoyl amino acetic acid, 2-2-benzyl-3-mercaptopropanamido acetic acid, n-rs-2-benzyl-3-mercaptopropanoyl-glycine, tiorphan
PubChem CID 3132
ChEBI CHEBI:9568
IUPAC Name 2-(2-benzyl-3-sulfanylpropanamido)acetic acid
SMILES OC(=O)CNC(=O)C(CS)CC1=CC=CC=C1

Specifications

Melting Point 135°C to 137°C
Color White
Quantity 25 mg
Beilstein 4872101
Solubility Information Soluble in ethanol at 50mg/ml
Formula Weight 253.32
Physical Form Powder
Chemical Name or Material DL-Thiorphan

Safety and Handling

RTECSNumber MC0596440
TSCA No
Recommended Storage Store at -20°C

RUO – Research Use Only