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ProSci Death Receptor 6 Recombinant Protein

Catalog No. 16594204
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0.05 mg
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16594204 0.05 mg
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Catalog No. 16594204 Supplier ProSci Supplier No. 913030050

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Description

Recombinant Protein

This recombinant protein can be used for biological assays. For research use only.

Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition, DR6 binds with N-APP, which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumor cell lines and can be induced by TNF- alpha.

Specifications

Accession Number O75509
For Use With (Application) Not Available
Gene ID (Entrez) 27242
Molecular Weight (g/mol) 34.62 kDa
Quantity 0.05 mg
Source Human Cells
Common Name tumor necrosis factor receptor superfamily member 21
Gene Symbol TNFRSF21
Product Type Recombinant Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag C-6 His tag
Content And Storage Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4°C to 7°C for 2-7 days. Aliquots of reconstituted samples are stable (at -20°C for 3 months.)
Form Lyophilized
Purity or Quality Grade >95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Synonym Tumor Necrosis Factor Receptor Superfamily Member 21, Death Receptor 6, CD358, TNFRSF21, DR6
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