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DCTN2 Polyclonal Antibody, Bethyl Laboratories
Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, X. laevis, X. tropicalis, Chicken and Bovine
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
Specifications
Specifications
| Antigen | DCTN2 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Formulation | TBS with 0.1% BSA and 0.09% sodium azide |
| Gene | DCTN2 |
| Gene Accession No. | Q13561, Q99KJ8 |
| Gene Alias | DCTN50, DYNAMITIN, RBP50, 50 kD dynein-associated polypeptide, 50 kDa dynein-associated polypeptide, dynactin complex 50 kD subunit, dynactin complex 50 kDa subunit, dynactin subunit 2, p50 dynamitin |
| Gene Symbols | Dctn2 |
| Host Species | Rabbit |
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