missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ DARC Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA520357
Description
A suggested positive control is mouse brain tissue lysate. PA5-20357 can be used with blocking peptide PEP-0477.
ACKR1 or DARC is an atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades resulting instead in chemokine sequestration, degradation, or transcytosis. ACKR1 is also known as an interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. It has a promiscuous chemokine-binding profile by interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. ACKR1 also acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1, TARC and for the malaria parasites P.vivax and P.knowlesi.Chemical Identifiers
| DARC | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| ACKR1 | |
| AA162249; ACKR1; Atypical chemokine receptor 1; atypical chemokine receptor 1 (Duffy blood group); CCBP1; CD234; CD234 antigen; CTA-134P22.3; DARC; Dfy; Duffy Antigen; Duffy antigen chemokine receptor; Duffy antigen receptor for chemokines; duffy antigen/chemokine receptor; Duffy blood group antigen; duffy blood group chemokine receptor; Duffy blood group, atypical chemokine receptor; Duffy blood group, chemokine receptor; ESTM35; FY; Fy Antigen; Fy glycoprotein; FYDuffy blood group; glycoprotein D; GPD; GPDWBCQ1; GpFy; HGNC:4035; OTTHUMP00000060081; Plasmodium vivax receptor; WBCQ1 | |
| ACKR1 | |
| Primary | |
| Antigen Affinity Chromatography |
| 1 mg/mL | |
| Immunohistochemistry, Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 0.02% sodium azide | |
| Q16570, Q9QUI6 | |
| 13349, 2532, 689105 | |
| A 16 amino acid peptide from near the carboxy terminus of human DARC. | |
| Antibody |
Specifications
| DARC | |
| Polyclonal | |
| Unconjugated | |
| ACKR1 | |
| AA162249; ACKR1; Atypical chemokine receptor 1; atypical chemokine receptor 1 (Duffy blood group); CCBP1; CD234; CD234 antigen; CTA-134P22.3; DARC; Dfy; Duffy Antigen; Duffy antigen chemokine receptor; Duffy antigen receptor for chemokines; duffy antigen/chemokine receptor; Duffy blood group antigen; duffy blood group chemokine receptor; Duffy blood group, atypical chemokine receptor; Duffy blood group, chemokine receptor; ESTM35; FY; Fy Antigen; Fy glycoprotein; FYDuffy blood group; glycoprotein D; GPD; GPDWBCQ1; GpFy; HGNC:4035; OTTHUMP00000060081; Plasmodium vivax receptor; WBCQ1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 13349, 2532, 689105 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q16570, Q9QUI6 | |
| ACKR1 | |
| A 16 amino acid peptide from near the carboxy terminus of human DARC. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |