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Invitrogen™ CYP1A2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5150271
Description
CYP1A2 Polyclonal Antibody for Western Blot, IHC (P), ICC/IF, ELISA
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.Specifications
| CYP1A2 | |
| Polyclonal | |
| Unconjugated | |
| Cyp1a2 | |
| aromatic compound inducible; aryl hydrocarbon hydroxylase; cholesterol 25-hydroxylase; CP12; CYP; Cyp1a1; Cyp1a2; Cyp1a-2; CYPD45; CYPIA2; Cytochrome P(3)450; cytochrome P-448; cytochrome P450 1A2; Cytochrome P450 4; cytochrome P450 family 1 subfamily A member 2; cytochrome P450 family 1 subfamily a polypeptide 1; Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d); cytochrome P450, 1a2; cytochrome P450, 1a2, aromatic compound inducible; cytochrome P450, family 1, subfamily A, polypeptide 2; cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2; Cytochrome P-450d; cytochrome P450-D; Cytochrome P450-P2; cytochrome P450-P3; dioxin-inducible P3-450; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P(3)450; P3-450; P-448; P450; P450 4; P450 form 4; P450(PA); P450-3; P-450d; P450-D; P450-P3; RATCYPD45; xenobiotic monooxygenase | |
| Rabbit | |
| Protein A | |
| RUO | |
| 13077, 1544, 24297 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.5 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 | |
| P00186, P04799, P05177 | |
| Cyp1a2 | |
| Recombinant Cytochrome P450 1A2 (CYP1A2) (Val192-Glu444). | |
| 200 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody |