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Invitrogen™ CXCL11 Recombinant Rabbit Monoclonal Antibody (23GB5640)
Description
CXCL11 Recombinant Monoclonal Antibody for ICC/IF, Western Blot
Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.
Specifications
Specifications
| Antigen | CXCL11 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 23GB5640 |
| Concentration | 0.7 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | CXCL11 |
| Gene Accession No. | O14625, Q9JHH5 |
| Gene Alias | betaR1; beta-R1; b-R1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 11; CXC; CXC motif chemokine; C-X-C motif chemokine 11; C-X-C motif chemokine ligand 11; Cxc11; CXCL; CXCL11; H174; Interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; IP9; IP-9; Itac; I-TAC; MGC102770; Scyb11; Scyb9b; small inducible cytokine B11; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; small-inducible cytokine B11 |
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