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PeproTech CXCL11 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Catalog No. 500P132BT25
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25 μg
50 μg
500 μg
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Catalog No. Quantity
500P132BT25 25 μg
500P132BT50 50 μg
502718681 500 μg
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Catalog No. 500P132BT25 Supplier PeproTech Supplier No. 500P132BT25UG
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Description

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human I-TAC (CXCL11). Anti-Human I-TAC (CXCL11)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human I-TAC (CXCL11) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human I-TAC (CXCL11) (500-P132) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human I-TAC (CXCL11). Western Blot: To detect hI-TAC by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hI-TAC is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P132BT-1MG will be provided as 2 x 500 μg

Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.

Specifications

Antigen CXCL11
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.1-1.0 mg/mL
Conjugate Biotin
Formulation PBS with no preservative
Gene CXCL11
Gene Accession No. O14625
Gene Alias betaR1; beta-R1; b-R1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 11; CXC; CXC motif chemokine; C-X-C motif chemokine 11; C-X-C motif chemokine ligand 11; Cxc11; CXCL; CXCL11; H174; Interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; IP9; IP-9; Itac; I-TAC; MGC102770; Scyb11; Scyb9b; small inducible cytokine B11; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; small-inducible cytokine B11
Gene Symbols CXCL11
Host Species Rabbit
Immunogen E.coli-derived Recombinant Human I-TAC (CXCL11).
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6373
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
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