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Invitrogen™ Cullin 3 Recombinant Rabbit Monoclonal Antibody (23GB1560)
Description
Cullin 3 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
Cullin 3 is a member of the family of human cullin genes (CUL 1, 2, 3, 4a, 4b, and 5) homologous to the S. cerevisiae cdc 53 gene. CUL 1 forms a complex with human p19 skp1 and F box protein p45 skp2. Together with cdc 53 (Known as Cul A), as three subunits, they form a ubiquitin ligase-controlling proteolysis of G1 cell cycle regulatory proteins. In contrast to CUL 1, CUL 2 does not associate with p19 skp1 and p45 skp2. Instead, CUL 2 forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongain C, Elongin B and VHL. The function of this association remains unknown.
Specifications
Specifications
| Antigen | Cullin 3 |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 23GB1560 |
| Concentration | 0.35 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | CUL3 |
| Gene Accession No. | B5DF89, Q13618, Q9JLV5 |
| Gene Alias | AI467304; AW146203; Cul3; CUL-3; cullin 3; cullin-3; KIAA0617; mKIAA0617; OTTHUMP00000203839; OTTHUMP00000203840; PHA2E |
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