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Invitrogen™ CUEDC1 Polyclonal Antibody
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Catalog No. PIPA555201
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100 μL
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PIPA555201 100 μL
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Catalog No. PIPA555201 Supplier Invitrogen™ Supplier No. PA555201
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VPGTGDANPA VSEDALFRDK LKHMGKSTRR KLFELARAFS EKTKMRKSKR KHLLKHQSLG AAASTANLLD DVEGHACDED FRGRRQEAPK VEEGLREGQ Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.

The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker.

Specifications

Antigen CUEDC1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CUEDC1
Gene Accession No. Q9NWM3
Gene Alias AI841487; C330016O16Rik; CUE domain containing 1; CUE domain-containing protein 1; Cuedc1; RGD1304861
Gene Symbols CUEDC1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CUEDC1. Recombinant protein control fragment (Product #RP-93488).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 404093
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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