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Invitrogen™ CTLA-4 Monoclonal Antibody (D4)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA565978
Description
CTLA-4 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.Specifications
| CTLA-4 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 | |
| P16410, Q9MYX7 | |
| CTLA4 | |
| Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) (Gly52-Cys211). | |
| 200 μL | |
| Primary | |
| Human, Rat, Pig | |
| Antibody | |
| IgG2b κ |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| D4 | |
| Unconjugated | |
| CTLA4 | |
| ALPS5; CD; CD152; CD152 antigen; CD152 isoform; CD152 protein; CD152 protein precursor; celiac disease 3; CELIAC3; Ctla4; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte associated protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; EGK_04712; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ly-56; sCTLA4; soluble form; transmembrane form | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 1493, 397286, 63835 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |