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Colistin sodium methanesulfonate
CAS: 8068-28-8 | C58H105N16Na5O28S5 | 1749.811 g/mol
$328.34 - $1703.52
Chemical Identifiers
| CAS | 8068-28-8 |
|---|---|
| Molecular Formula | C58H105N16Na5O28S5 |
| Molecular Weight (g/mol) | 1749.811 |
| MDL Number | MFCD00130824 |
| InChI Key | IQWHCHZFYPIVRV-KLWRPAJRSA-I |
| Synonym | Colimycin sodium methanesulfonate; Polymyxin E sodium methanesulfonate |
| PubChem CID | 131668505 |
| IUPAC Name | pentasodium;(6S)-N-[(2R)-1-[[(2R,3S)-3-hydroxy-1-[[(2S)-1-[[(3S,6S,9S,12S,15R,18S,21S)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-8,17,20-trioxido-2,5,11,14-tetraoxo-6,9,18-tris[2-(sulfomethylamino)ethyl]-1,4,7,10,13,16,19-heptazacyclotricosa-7,16, |
| SMILES | CCC(C)CCCCC(=NC(CCNCS(=O)(=O)O)C(=O)NC(C(C)O)C(=O)NC(CCNCS(=O)(=O)O)C(=NC1CCNC(=O)C(NC(=O)C(N=C(C(NC(=O)C(NC(=O)C(N=C(C(N=C1[O-])CCNCS(=O)(=O)O)[O-])CC(C)C)CC(C)C)CCNCS(=O)(=O)O)[O-])CCNCS(=O)(=O)O)C(C)O)[O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+] |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6669803
|
Thermo Scientific Chemicals
J6669803 |
1 g |
Each for $328.34
|
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AAJ6669806
|
Thermo Scientific Chemicals
J6669806 |
5 g |
Each for $1,703.52
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Description
Colistin sodium methanesulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination. It is used to study effective treatments of P. aeruginosa infections in cystic fibrosis patients and to study the pharmacokinetics and BAL concentration of colistin in critically ill patients
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilityFreely soluble in water
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Chemical Identifiers
| 8068-28-8 | |
| 1749.811 | |
| IQWHCHZFYPIVRV-KLWRPAJRSA-I | |
| 131668505 | |
| CCC(C)CCCCC(=NC(CCNCS(=O)(=O)O)C(=O)NC(C(C)O)C(=O)NC(CCNCS(=O)(=O)O)C(=NC1CCNC(=O)C(NC(=O)C(N=C(C(NC(=O)C(NC(=O)C(N=C(C(N=C1[O-])CCNCS(=O)(=O)O)[O-])CC(C)C)CC(C)C)CCNCS(=O)(=O)O)[O-])CCNCS(=O)(=O)O)C(C)O)[O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+] |
| C58H105N16Na5O28S5 | |
| MFCD00130824 | |
| Colimycin sodium methanesulfonate; Polymyxin E sodium methanesulfonate | |
| pentasodium;(6S)-N-[(2R)-1-[[(2R,3S)-3-hydroxy-1-[[(2S)-1-[[(3S,6S,9S,12S,15R,18S,21S)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-8,17,20-trioxido-2,5,11,14-tetraoxo-6,9,18-tris[2-(sulfomethylamino)ethyl]-1,4,7,10,13,16,19-heptazacyclotricosa-7,16, |
Specifications
| Colistin Sodium Methanesulfonate | |
| 8068-28-8 | |
| 1 g | |
| MFCD00130824 | |
| Colimycin sodium methanesulfonate; Polymyxin E sodium methanesulfonate | |
| IQWHCHZFYPIVRV-KLWRPAJRSA-I | |
| pentasodium;(6S)-N-[(2R)-1-[[(2R,3S)-3-hydroxy-1-[[(2S)-1-[[(3S,6S,9S,12S,15R,18S,21S)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-8,17,20-trioxido-2,5,11,14-tetraoxo-6,9,18-tris[2-(sulfomethylamino)ethyl]-1,4,7,10,13,16,19-heptazacyclotricosa-7,16, | |
| 131668505 | |
| Colistin sodium methanesulfonate |
| Powder | |
| White to Yellow | |
| C58H105N16Na5O28S5 | |
| 14,2479 | |
| Freely soluble in water | |
| CCC(C)CCCCC(=NC(CCNCS(=O)(=O)O)C(=O)NC(C(C)O)C(=O)NC(CCNCS(=O)(=O)O)C(=NC1CCNC(=O)C(NC(=O)C(N=C(C(NC(=O)C(NC(=O)C(N=C(C(N=C1[O-])CCNCS(=O)(=O)O)[O-])CC(C)C)CC(C)C)CCNCS(=O)(=O)O)[O-])CCNCS(=O)(=O)O)C(C)O)[O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+] | |
| 1749.811 | |
| 1759.89 |
Safety and Handling
EINECSNumber : 232-516-9
RTECSNumber : GH1650000
TSCA : Yes
storageNote1 : 2° to 8°C
Recommended Storage : Keep cold
RUO – Research Use Only