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Invitrogen™ Coilin Polyclonal Antibody
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Catalog No. PIPA5100038
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PIPA5100038 100 μL
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Catalog No. PIPA5100038 Supplier Invitrogen™ Supplier No. PA5100038
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Coilin.

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

Specifications

Antigen Coilin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene COIL
Gene Accession No. P38432, Q5SU73
Gene Alias C79982; CLN80; COIL; Coilin; coilin p80; hypothetical protein LOC507580; LOW QUALITY PROTEIN: coilin; nuclear phosphoprotein of Cajal body; p80; p80-coilin; wu:fb08h11
Gene Symbols COIL
Host Species Rabbit
Immunogen A synthesized peptide derived from human COIL(Accession P38432), corresponding to amino acid residues G371-H421.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12812, 50998, 8161
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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