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Invitrogen™ COG8 Polyclonal Antibody

Description
Recommended positive controls: 293T, A431, Raji. Predicted reactivity: Mouse (89%), Rat (91%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance.
Specifications
Specifications
| Antigen | COG8 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | COG8 |
| Gene Accession No. | Q96MW5 |
| Gene Alias | BB235941; C87832; CDG2H; COG complex subunit 8; Cog8; Component of oligomeric Golgi complex 8; conserved oligomeric golgi complex component 8; conserved oligomeric Golgi complex protein 8; conserved oligomeric Golgi complex subunit 8; dependent on RIC1; DOR1; MNCb-5704 |
| Gene Symbols | COG8 |
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