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  6. Invitrogen™ Cofilin Monoclonal Antibody (C12), Invitrogen™

Invitrogen™ Cofilin Monoclonal Antibody (C12), Invitrogen™
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Catalog No. FEMA551063
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200 μL
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FEMA551063 200 μL
FEMA551064 20 μL
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Catalog No. FEMA551063 Supplier Invitrogen™ Supplier No. MA551063
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Description

Mouse Monoclonal Antibody

Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.

Specifications

Antigen Cofilin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone C12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene CFL1
Gene Accession No. P10668, P23528, Q5E9F7
Gene Alias 18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18
Gene Symbols CFL1
Host Species Mouse
Immunogen Recombinant Human CFL1 protein, Ser3-Leu161 (Accession #P23528).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1072, 445532, 534553
Target Species Bovine, Human, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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