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Invitrogen™ Claudin 1 Polyclonal Antibody (MH25)
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ 717800
Description
This antibody reacts with the ~ 22 kDa Claudin-1 protein. Reactivity was confirmed by western blotting and immunofluorescence. Positive controls include MDCK cells (dog), Caco-2cells (human), mouse liver, rat liver, and rat kidney. NOTE: This antibody strongly cross reacts with the Claudin-3 protein. It has been observed in western blotting inhibition studies using Caco-2 cell lysates, that this antibody is inhibited by addition of Claudin-3 peptide. For a Claudin-1 specific antibody that does not cross-react with Claudin-3, please order Cat. No. 519000 (Rb x Claudin-1) instead.
Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.Chemical Identifiers
| Claudin 1 | |
| 0.25 mg/mL | |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| O88551, O95832, P56745 | |
| 12737, 608207, 65129, 9076 | |
| A synthetic peptide derived from the C-terminus of the human/mouse Claudin-1 protein. | |
| Antibody |
| MH25 | |
| -20°C | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat, Canine | |
| CLDN1 | |
| AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944 | |
| CLDN1 | |
| Primary | |
| Antigen affinity chromatography |
Specifications
| Claudin 1 | |
| Polyclonal | |
| 0.25 mg/mL | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| O88551, O95832, P56745 | |
| CLDN1 | |
| A synthetic peptide derived from the C-terminus of the human/mouse Claudin-1 protein. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat, Canine | |
| Antibody | |
| IgG |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| MH25 | |
| Unconjugated | |
| CLDN1 | |
| AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 12737, 608207, 65129, 9076 | |
| -20°C | |
| Liquid |