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Invitrogen™ CIRBP Polyclonal Antibody

Description
CIRBP Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)
CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.
Specifications
Specifications
| Antigen | CIRBP |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Gene | CIRBP |
| Gene Accession No. | P60824, Q14011 |
| Gene Alias | A18 hnRNP; A18HNRNP; CIRBP; CIRP; cold inducible RNA binding protein; cold inducible RNA-binding protein; cold-inducible RNA-binding protein; glycine-rich RNA binding protein; glycine-rich RNA-binding protein CIRP; R74941; testicular tissue protein Li 39 |
| Gene Symbols | CIRBP |
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