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Invitrogen™ CDC45L Monoclonal Antibody (6H6)
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Catalog No. PIMA549196
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100 μg
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Catalog No. Quantity
PIMA549196 100 μg
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Catalog No. PIMA549196 Supplier Invitrogen™ Supplier No. MA549196
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Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human K562 whole cell, human HL-60 whole cell, human HEK293 whole cell. IHC: human ovarian cancer tissue, human breast cancer tissue, human esophageal squamous carcinoma tissue, human pancreatic cancer tissue, human prostate cancer tissue, rat testis tissue, mouse thymus tissue. Flow: 293T cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenylation sites of this gene are reported.

Specifications

Antigen CDC45L
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 6H6
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene Cdc45
Gene Accession No. O75419, Q9Z1X9
Gene Alias CDC 45; CDC 45L; Cdc45; CDC45 cell division cycle 45 homolog; CDC45 like; CDC45L; CDC45L2; CDC45-related protein; Cell division control protein 45 homolog; cell division cycle 45; cell division cycle 45 homolog; cell division cycle 45-like 2; human CDC45; PORC PI 1; PORC-PI-1; UNQ374/PRO710
Gene Symbols Cdc45
Host Species Mouse
Immunogen E. coli-derived human CDC45L recombinant protein (Position: E166-A431).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12544, 287961, 8318
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG1
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