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Invitrogen™ CD68 Polyclonal Antibody
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Catalog No. PIPA583940
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100 μL
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Catalog No. Quantity
PIPA583940 100 μL
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Catalog No. PIPA583940 Supplier Invitrogen™ Supplier No. PA583940
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SPTSKETIGD YTWTNGSQPC VHLQAQIQIR VMYTTQGGGE AWGISVLNPN KTKVQGSCEG AHPHLLLSFP YG Highest antigen sequence indentity to the following orthologs: Mouse - 76%, Rat - 76%.

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Specifications

Antigen CD68
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Cd68
Gene Accession No. P34810
Gene Alias CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Gene Symbols Cd68
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CD68. Recombinant protein control fragment (Product #RP-100954).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 968
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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