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  6. Invitrogen™ CD42d Monoclonal Antibody (1C2), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Invitrogen™ CD42d Monoclonal Antibody (1C2), Alexa Fluor™ 488, eBioscience™, Invitrogen™
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Catalog No. 53042182
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53042182 100 μg
53042180 25 μg
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Catalog No. 53042182 Supplier Invitrogen™ Supplier No. 53042182

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Description

Armenian Hamster Monoclonal Antibody

Description: The monoclonal antibody 1C2 recognizes mouse and rat CD42d, a single transmembrane protein also known as platelet glycoprotein V (GPV). CD42d interacts with CD42a, CD42b and CD42c to form the receptor for von willebrand factor and thrombin. This functional complex plays a role in platelet adhesion. Expression of CD42d (unlike other markers such as CD41) is restricted to resting platelets and megakaryocytes and therefore is a good marker for development of megakaryocytes. Applications Reported: This 1C2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 1C2 antibody has been tested by flow cytometric analysis of mouse platelets. This may be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser

Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.

Specifications

Antigen CD42d
Applications Flow Cytometry
Classification Monoclonal
Clone 1C2
Concentration 0.5 mg/mL
Conjugate Alexa Fluor 488
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Gp5
Gene Accession No. O08742, O08770
Gene Alias CD42d; Glycoprotein 5; glycoprotein 5 (platelet); glycoprotein 5, platelet; glycoprotein V (platelet); glycoprotein V platelet; GP5; GPV; Platelet glycoprotein 5; platelet glycoprotein V; Platelete glycoprotein 5; Platelets GP V; PLGPV
Gene Symbols Gp5
Host Species Armenian Hamster
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14729, 25259
Target Species Mouse, Rat
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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