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  6. Invitrogen™ CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH1), NovaFluor™ Red 685, eBioscience™, Invitrogen™

Invitrogen™ CD274 (PD-L1, B7-H1) Monoclonal Antibody (MIH1), NovaFluor™ Red 685, eBioscience™, Invitrogen™

Catalog No. p-200088588
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100 Tests
25 Tests
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Catalog No. Quantity
H089T02R02A 25 Tests
H089T03R02A 100 Tests
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Catalog No. H089T02R02A Supplier Invitrogen™ Supplier No. H089T02R02A
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Description

Mouse Monoclonal Antibody

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.

Specifications

Antigen CD274 (PD-L1, B7-H1)
Applications Flow Cytometry
Classification Monoclonal
Clone MIH1
Concentration 0.8 μg/Test
Conjugate NovaFluor Red 685
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Cd274
Gene Accession No. Q9NZQ7
Gene Alias A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1
Gene Symbols Cd274
Host Species Mouse
Purification Method Affinity chromatography
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29126
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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