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Invitrogen™ CD177 Polyclonal Antibody
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Catalog No. PIPA5100712
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100 μL
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PIPA5100712 100 μL
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Catalog No. PIPA5100712 Supplier Invitrogen™ Supplier No. PA5100712
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CD177.

CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).

Specifications

Antigen CD177
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CD177
Gene Accession No. Q8N6Q3
Gene Alias 1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181
Gene Symbols CD177
Host Species Rabbit
Immunogen A synthesized peptide derived from human CD177(Accession Q8N6Q3), corresponding to amino acid residues L298-A348.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 499099, 57126
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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