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Invitrogen™ Caspase 6 Recombinant Rabbit Monoclonal Antibody (23GB1225)
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Catalog No. MA570441
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100 μL
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MA570441 100 μL
MA570442 20 μL
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Catalog No. MA570441 Supplier Invitrogen™ Supplier No. MA570441

Rabbit Recombinant Monoclonal Antibody

Caspase 6 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Specifications

Antigen Caspase 6
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB1225
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Casp6
Gene Accession No. O08738, O35397, P55212
Gene Alias apoptotic protease MCH-2, CASP6, CASP-6, caspase 6, caspase 6, apoptosis-related cysteine peptidase, caspase 6, apoptosis-related cysteine protease, caspase-6, Caspase-6 subunit p11, Caspase-6 subunit p18, mCASP-6, MCH2
Gene Symbols Casp6
Host Species Rabbit
Immunogen A synthesized peptide derived from human (171-198) Caspase-6.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12368, 83584, 839
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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