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  6. Invitrogen™ Caspase 10 Recombinant Rabbit Monoclonal Antibody (23GB3330)

Invitrogen™ Caspase 10 Recombinant Rabbit Monoclonal Antibody (23GB3330)
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Catalog No. MA552554
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MA552554 100 μL
MA552555 20 μL
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Catalog No. MA552554 Supplier Invitrogen™ Supplier No. MA552554
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Description

Rabbit Recombinant Monoclonal Antibody

Caspase 10 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

Antigen Caspase 10
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB3330
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CASP10
Gene Accession No. Q92851
Gene Alias ALPS2; Apoptotic protease Mch-4; CASP10; CASP-10; caspase 10; caspase 10 apoptosis-related cysteine peptidase; caspase 10, apoptosis-related cysteine peptidase; caspase 10, apoptosis-related cysteine protease; caspase-10; Caspase-10 subunit p12; Caspase-10 subunit p23/17; FADD-like ICE2; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4; interleukin-1B-converting enzyme 2; MCH4
Gene Symbols CASP10
Host Species Rabbit
Immunogen A synthetic peptide of human Caspase-10 (250-450AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 843
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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