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Invitrogen™ Cardiac Troponin T Monoclonal Antibody (7E7)
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Catalog No. PIMA120879
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Quantity:
200 μg
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Catalog No. Quantity
PIMA120879 200 μg
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Catalog No. PIMA120879 Supplier Invitrogen™ Supplier No. MA120879

Description

Mouse Monoclonal Antibody

MA1-20879 detects Cardiac Troponin T in Human samples.

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.

Specifications

Antigen Cardiac Troponin T
Applications Affinity Purification, ELISA
Classification Monoclonal
Clone 7E7
Concentration 5.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene TNNT2
Gene Accession No. P45379
Gene Alias alternatively spliced; cardiac muscle troponin T; cardiac TnT; cardiac troponin 2; cardiac troponin 2 adult #1 isoform; cardiac troponin 2 adult #2 isoform; cardiac troponin 2 embryonic #1 isoform; cardiac troponin 2 embryonic #2 isoform; cardiac troponin 2, exclusion exon 6 #1 isoform; cardiac troponin 2, exclusion exon 6 #2 isoform; cardiac troponin T; cardiac troponin T form I; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T isoform I; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; CMD1D; CMH2; CMPD2; cTnT; Ctt; CTTG; LVNC6; MGC3889; RATCTTG; RCM3; TNNT2; Tnnt3; Tnt; TnTc; troponin T; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin T splicing mutant isoform 2; troponin T type 2 (cardiac); troponin T, cardiac muscle; Troponin T, cardiac muscle isoforms; Troponin T2; troponin T2, cardiac; troponin T2, cardiac type; truncated cardiac troponin T
Gene Symbols TNNT2
Host Species Mouse
Immunogen Human Tn complex.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7139
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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