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Invitrogen™ Cardiac Troponin T Monoclonal Antibody (1G1)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA517192
Description
MA5-17192 targets troponin T2 in indirect ELISA, FACS and WB applications and shows reactivity with Human samples. The MA5-17192 immunogen is purified recombinant fragment of human troponin T2 expressed in E. Coli. MA5-17192 detects troponin T2 which has a predicted molecular weight of approximately 36kDa.
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.Specifications
| Cardiac Troponin T | |
| Monoclonal | |
| Conc. Not Determined | |
| ascites with 0.03% sodium azide | |
| P45379 | |
| TNNT2 | |
| Purified recombinant fragment of human troponin T2 expressed in E. Coli. | |
| RUO | |
| 7139 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Flow Cytometry, Western Blot | |
| 1G1 | |
| Unconjugated | |
| TNNT2 | |
| alternatively spliced; cardiac muscle troponin T; cardiac TnT; cardiac troponin 2; cardiac troponin 2 adult #1 isoform; cardiac troponin 2 adult #2 isoform; cardiac troponin 2 embryonic #1 isoform; cardiac troponin 2 embryonic #2 isoform; cardiac troponin 2, exclusion exon 6 #1 isoform; cardiac troponin 2, exclusion exon 6 #2 isoform; cardiac troponin T; cardiac troponin T form I; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T isoform I; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; CMD1D; CMH2; CMPD2; cTnT; Ctt; CTTG; LVNC6; MGC3889; RATCTTG; RCM3; TNNT2; Tnnt3; Tnt; TnTc; troponin T; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin T splicing mutant isoform 2; troponin T type 2 (cardiac); troponin T, cardiac muscle; Troponin T, cardiac muscle isoforms; Troponin T2; troponin T2, cardiac; troponin T2, cardiac type; truncated cardiac troponin T | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |