missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Specifications
| Accession Number | 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; mast cell growth factor; Mgf; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF |
|---|---|
| Assay Range | 0.065 to 16 ng/mL |
| Assay Sensitivity | 0.065 ng/mL |
| Conjugate | HRP |
| Product Type | ELISA |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
EC16RBX5
|
Invitrogen™
EC16RBX5 |
5 x 96 Tests |
N/A
|
|
|||||
|
EC16RB
|
Invitrogen™
EC16RB |
96 Tests |
N/A
|
|
|||||
Description
Canine SCF/KITLG quantitates canine SCF/KITLG in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine SCF/KITLG.
Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.Specifications
| 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; mast cell growth factor; Mgf; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF | |
| 0.065 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| KITLG | |
| <10 | |
| HRP | |
| Plasma 50 μL, Serum 50 μL, Supernatant 50 μL | |
| SCF | |
| 4 hrs 45 mins |
| 0.065 to 16 ng/mL | |
| HRP | |
| Plasma, Serum, Supernatant | |
| 403507 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| RUO | |
| 2°C to 8°C | |
| 1 hrs 20 mins |